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News

Nanna Therapeutics Awarded £829,892 Innovate UK Grant

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Nanna Therapeutics Awarded £829,892 Innovate UK Grant to Discover Novel Drugs Leveraging its Nanoscale Medicines Discovery Engine Expands Scientific Advisory Board with Appointment of Prof. David Spring Cambridge, UK, 9th April 2019 – Nanna Therapeutics Ltd, a biotechnology company developing novel drugs to combat age-related diseases, particular those caused by mitochondrial dysfunction, today announced that […]

What we do

Nanna Therapeutics is a 21st century drug discovery company addressing age-related diseases for which others are failing to provide effective treatments.  These include mitochondrial, neurodegenerative, cardiovascular/metabolic, joint/tissue disease as well as cancer.

A New VISION for Medicines

Our Aims:

  • To create medicines which target the cause of disease
  • To unlock treatments for rare as well as challenging prevalent diseases
  • To reduce the time and cost of delivering new therapies
  • To make healthy aging a reality

Therapy Areas

Nanna Therapeutics are targeting fundamental cellular processes to create drugs to treat age-related diseases and improve longevity.  Such drugs include those to combat debilitating neurodegenerative, inflammatory, cardiovascular and metabolic diseases as well as many cancers. With a strong focus on mitochondria, the energy source in every cell, we can target the fundamental causes of many age-related diseases. Through this approach we can also address debilitating, life-limiting mitochondrial diseases for which there are currently few effective therapies.

Technology

Nanna Therapeutics has developed a tightly integrated set of proprietary technologies that radically disrupt current methods of creating new medicines. This Totally Integrated Medicines Engine (TIME) has been devised to answer the needs of drug discovery and development scientists utilising the best in 21st century technologies of microfluidics, nanofabrication and artificial intelligence.

Partners

Management Team

David Williams, PhD
Chief Executive Officer

Alex Alanine, PhD
Chief Operating Officer

Stuart Wood, PhD
Chief Technology Officer

Nicki Thompson, PhD
Board Chair

Scientific Advisory Board

Prof Sir Doug Turnbull
Director Wellcome Trust Centre
for Mitochondrial Research
Jane Osbourn, PhD
VP Research and Development
MedImmune
Prof Mervyn Bibb FRS
Emeritus Fellow
John Innes Centre
Prof Nicholas Turner
Professor of Chemical Biology
Manchester University
Prof Pietro Lio
Professor of Computational Biology
University of Cambridge
Prof Dave Spring
Professor of Chemistry and Chemical Biology
University of Cambridge

News

Nanna Therapeutics Awarded £829,892 Innovate UK Grant

Posted Posted in News, Uncategorized

Nanna Therapeutics Awarded £829,892 Innovate UK Grant to Discover Novel Drugs Leveraging its Nanoscale Medicines Discovery Engine Expands Scientific Advisory Board with Appointment of Prof. David Spring Cambridge, UK, 9th April 2019 – Nanna Therapeutics Ltd, a biotechnology company developing novel drugs to combat age-related diseases, particular those caused by mitochondrial dysfunction, today announced that […]

Addition to Scientific Advisory Board and Company Name Change

Posted Posted in News

Cambridge, UK, 14th August 2018 – Bactevo Ltd. announced today that Professor Pietro Lio of the Computer Laboratory in Cambridge University has joined its Scientific Advisory Board. Pietro brings a wealth of skills from the disciplines of bioinformatics and machine learning. During his distinguished career, Pietro has pioneered the development and testing of novel methodologies […]

@nannathera

Meet Us

Nanna Therapeutics will be at the following meetings and conferences:

  • 13-16 January 2020 – J.P. Morgan 38th Annual Healthcare Conference, San Francisco, California, USA
  • 20-21  November 2019 – Jefferies Healthcare Conference, London, UK
  • 3-6 June 2019 – Bio 2019, Philadelphia, USA
  • 6-10 January 2019 – J.P. Morgan 37th Annual Healthcare Conference, San Francisco, California US
  • 21 March 2019 – Bioinformatics Strategy Meeting EU 2019, London, UK
  • 18-19 March 2019 – Drug Discovery Chemistry, London, UK
  • 17 – 22 March 2019 – Gordon Research Conference: Mitochondria in Health and Disease
2018 Meetings

Careers

Computational Chemist, Drug Discovery - *Position Closed *
Overview

Nanna Therapeutics Ltd. is a Cambridge, UK based biotech developing ground-breaking technologies to revolutionise drug discovery. As we continue to grow, we are seeking an experienced computational chemist to join our dynamic, multi-disciplinary team, focused on developing novel technology and drug discovery platform. Our ideal candidate is a self-motivated innovative scientist with the ability to work across disciplines and interact daily with a diverse multidisciplinary team. As well as keen to expand their skill sets. This will be an exciting opportunity to join a dynamic company with a great culture poised for growth at the cutting edge of drug discovery.

We are seeking a scientist with experience in some or all the following key areas:

1. Qualification, Knowledge and Experience
  • You will have a PhD or 3+ years of industrial experience in the field of Cheminformatics
  • You should have knowledge to build and develop cheminformatics algorithms using chemical descriptors and property predictors, including their appropriate application.
To do this, you will have demonstrated skills
  • In Java and Python
  • You should be familiar with cheminformatic libraries such as RDKit or CDK
  • You will be experienced with good software development practices
  • Proficiency with handling large data sets and developing robust analysis pipelines
  • Experience working with relational or NoSQL databases
  • Knowledge of common data formats such as JSON
2. Essential Skills / Attributes
  • Good interpersonal/communication skills, effective team working.
  • High level of attention to detail, as well as demonstrated ability to work independently.
  • Passion for science and a problem-solving attitude with a creative and inventive flare.
  • Adaptable and quick to learn capable of working to tight deadlines and exacting standards.
3. Desirable Experience
  • Building and manipulating Knime work-flows
  • Knowledge of SMARTS in the context of reaction enumerations
  • Use of third-party chemistry software such as Cresset, MOE, Spotfire
  • Experience of bioinformatics and familiarity with genome data
  • Experience developing and applying Machine Learning methods to complex datasets
Applicants should submit a CV and covering letter by email to jobs@nannatherapeutics.com. Closing date will be 9am on the 14th of June, 2019.
Degree Apprenticeship Bioinformatics BSc (Hons) - *Position Closed *

Nanna Therapeutics Ltd. is a Cambridge based biotech developing ground-breaking technologies to revolutionise drug discovery. Our main focus is leveraging our technology to create medicines for the treatment of mitochondrial and age-related diseases

Anglia Ruskin University story starts in 1858 and became Anglia Ruskin University in 2005. It modern-day campus is still at the heart of Cambridge.

Specification

We are seeking someone who is enthusiastic, self-reliant and has a keen interest in computing, biology, and chemistry and for a 4 year BSc Bioinformatics honours degree apprenticeship. Degree apprenticeships are similar to higher apprenticeships, but differ in that they provide an opportunity to gain a full bachelor's degree (Level 6). The apprenticeship is in collaboration with Anglia Ruskin University and will be 4 days a week working at Nanna Therapeutics and 1 day at the University. At the end of the apprenticeship, the apprentice will have a BSc Honours degree, 4 years work experience and no student loan debt.

Essential Skills / Attributes
  • An  A Level in either statistics, computer science, applied maths, physics or another numerate discipline. An equivalent qualification would be acceptable.

  • 112 UCAS points or equivalent.

  • 4 GCSEs at Grade B/Grade 6, including Maths and English.

  • If English is not your first language, you will be expected to demonstrate a certified level of proficiency of at least IELTS 6.5 or equivalent.

Desirable Skills / Attributes

  • Biology A level or equivalent

  • Chemistry A level or equivalent

  • Programming experience

Please send a CV and covering letter by email to jobs@nannatx.com before the 31st of May 2019. Please no agencies or recruiters.
Scientist Synthetic Chemistry - *Position Closed *
Nanna Therapeutics Ltd. is a Cambridge, UK based biotech developing ground-breaking technologies to revolutionise drug discovery and we are leveraging this technology to treat mitochondrial and age-related diseases. As we continue to grow, we are seeking a skilled, enthusiastic scientist with experience in synthetic chemistry who can help grow our platform, utilising cutting edge technology to optimise reaction chemistry and help us build new, huge novel encoded chemistry libraries. Importantly you must be able to work across disciplines and function effectively as part of a multidisciplinary team. Each member of our team is committed to continuous learning, expanding their skills base and growing expertise, both on the job and through specific courses, conferences and training events with the chance to adopt additional roles and responsibilities as they develop. The ideal candidate will have a broad synthetic chemistry knowledge on which to call and experience with array or medicinal chemistry or encoded library technologies would be advantageous. However, a problem solver who can help develop new methods and techniques and is keen to learn, who will readily develop their skills and the develop the company’s capabilities by providing new ideas is ideal. The role is an exciting opportunity to join a dynamic company poised for growth at the cutting edge of drug discovery and help grow our chemistry team, within our multidisciplinary research group, developing both a new generation of drug discovery platforms and drugs to treat patients. Specification We are currently seeking a research scientist to join us with experience in Synthetic Chemistry Qualification BTec/HND/BSc/MSc in job-related field of study and 3+ years of relevant laboratory experience Or PhD in a relevant field with at least 1 year in an industrial setting or post-doctoral experience Knowledge and Experience
  • We expect that the successful candidate will have:
  • A strong background in synthetic chemistry and experience with a wide range of reaction types and developing novel methods and synthetic routes.
  • Use of analytical tools for reaction optimisation and trouble-shooting, HPLC, LC-MS, NMR, UV instruments and interpreting resulting analytical data.
  • Proven track record of working with other disciplines and teams in a constructive and collaborative manner
In addition, it would be desirable that the successful candidate has
  • Experience in medicinal or combinatorial chemistry
  • Experience in creating compound arrays, split and mix, encoded libraries or solid supported chemistry would be an advantage.
Essential Skills / Attributes
  • Passion for science together with a ‘can-do’ problem-solving approach
  • Ability and desire to learn new skills quickly and apply new concepts and techniques
  • Good interpersonal/communication skills able to work effectively across disciplines
  • An adaptable team player capable of working to tight deadlines and exacting standards
Strong organisational skills including ability to prioritise and work under pressure Please send a CV and covering letter by email to jobs@nannatx.com, although the closing date is April 15th we will review CVs weekly and call desirable candidates for interview as they come in and keep the job open until successful recruitment. Please no agencies or recruiters.
Research Scientist - Molecular Cell Biology - *Position Closed *

Overview

Nanna Therapeutics Ltd. is a Cambridge, UK based biotech developing ground-breaking technologies to revolutionise drug discovery and we are leveraging this technology to treat mitochondrial and age-related diseases.

As we continue to grow, we are seeking a skilled, enthusiastic scientist with experience in Molecular Cell Biology techniques and importantly the ability to work across disciplines and function effectively as part of a multidisciplinary team. Each member of our team is committed to continuous learning, expanding their skills base and growing expertise, both on the job and through specific courses, conferences and training events with the chance to adopt additional roles and responsibilities as they develop.

The role is an exciting opportunity to join a dynamic company poised for growth at the cutting edge of drug discovery and help grow our biology team, developing both a new generation of drug discovery platforms and drugs to treat patients.

Specification

We are currently seeking a research scientist to join us working on our microfluidic drug discovery platform.

1. Qualification, Knowledge and Experience

  • BTec/HND/BSc/MSc in job-related field of study and 3+ years of relevant laboratory experience, or a PhD in a relevant field.
  • Experience in one or more of the following techniques is required;
  • Mitochondrial Biology
  • Mammalian Cell Engineering
  • Flow-Cytometry/FACS/Single Cell analysis techniques
  • Molecular Biology techniques including qPCR, NGS and assay development
  • Experience or knowledge of drug discovery or biotechnology industry would be beneficial, but a desire to develop drugs and learn new skills is essential.

2. Essential Skills / Attributes

  • High level of attention to detail.
  • Passion for science together with a ‘can-do’ problem-solving approach.
  • Ability and desire to learn new skills quickly and apply new concepts and techniques.
  • Good interpersonal/communication skills able to work effectively across disciplines.
  • An adaptable team player capable of working to tight deadlines and exacting standards.
  • Strong organisational skills including ability to prioritise and work under pressure.
  • Ability to follow and create standard protocols and record data accurately.
  • Respect for confidentiality and integrity.

Please send a CV and covering letter by email to jobs@nannatherapeutics.com. Direct applicants only please, no agencies.Closing date will be Monday the 11th of February at 9am.

Scientist Synthetic Chemistry - *Position Closed*

Overview

Nanna Therapeutics Ltd. is a Cambridge, UK based biotech developing ground-breaking technologies to revolutionise drug discovery. As we continue to grow, we are seeking a scientist to join our dynamic, multi-disciplinary team, focused on designing, making and expanding the synthetic repertoire of our encoded synthetic chemistry libraries for application in our totally integrated drug discovery platform.

We are seeking hard working innovative and inventive scientist with the ability to work across disciplines and function effectively as part of a diverse multidisciplinary team. Each member of our team is committed to continuous learning, expanding their skills base and growing expertise, both on the job and through specific courses and training as required.

This will be an exciting opportunity to join a dynamic company poised for growth at the cutting edge of drug discovery.

Specification

We are seeking a scientist with experience in the following key areas:

Qualification, Knowledge and Experience

  • Experience in either synthetic, medicinal or combinatorial chemistry with 3+ years in industry or some postdoctoral experience.
  • A strong background in synthetic chemistry and experience with a wide range of reaction types and developing novel methods and synthetic routes.
  • Use of analytical tools for reaction optimisation and trouble-shooting, HPLC, LC-MS, NMR, UV instruments and interpreting resulting analytical data.
  • Experience in creating compound arrays, split and mix, encoded libraries or solid supported chemistry would be an advantage.
  • Experience with one of the following techniques is desirable: polymer or surfactant synthesis, microfluidics, computational chemistry, performing biological assays.
  • Experience with one of the following techniques is desirable: microfluidics, computational chemistry, DNA sequencing, performing biological assays.

2. Essential Skills / Attributes

  • Good interpersonal/communication skills, effective team working.
  • High level of attention to detail, as well as demonstrated ability to work independently.
  • Passion for science and a problem-solving attitude with a creative and inventive flare.
  • Adaptable, capable of working to tight deadlines and exacting standards.
  • Strong organisational skills with an ability to prioritise and work under pressure.
  • Demonstrated ability to learn quickly, applying new concepts and techniques.

Applicants should submit a CV and covering letter by email to jobs@nannatherapeutics.com Closing date will be 9am on the 14th of January 2019.

Associate Synthetic Chemist - *Position Closed*

Overview

Nanna Therapeutics Ltd. is a Cambridge, UK based biotech developing ground-breaking technologies to revolutionise drug discovery. As we continue to grow, we are seeking a scientist to join our dynamic, multi-disciplinary team, focused on designing, making and expanding the synthetic repertoire of our encoded synthetic chemistry libraries for application in our totally integrated drug discovery platform.

We are seeking hard working innovative and inventive scientist with the ability to work across disciplines and function effectively as part of a diverse multidisciplinary team. Each member of our team is committed to continuous learning, expanding their skills base and growing expertise, both on the job and through specific courses and training as required.

This will be an exciting opportunity to join a dynamic company poised for growth at the cutting edge of drug discovery.

Specification

We are seeking a scientist with experience in the following key areas:

Qualification, Knowledge and Experience

  • Practical experience in either synthetic, medicinal or combinatorial chemistry with at least a BSc or MSc in chemistry and ideally 1+ year of industrial experience.
  • A background in synthetic chemistry and experience with a wide range of reaction types and developing novel methods and synthetic routes.
  • Use of analytical tools for reaction optimisation and trouble-shooting, e.g. HPLC, LC-MS, NMR, UV instruments and interpreting resulting analytical data.
  • Knowledge of creating compound arrays, split and mix, encoded libraries or solid supported chemistry would be an advantage.

2. Essential Skills / Attributes

  • Good interpersonal/communication skills, effective team working skills.
  • High level of attention to detail, as well as demonstrated ability to work independently with minimal supervision.
  • Passion for science and a problem-solving attitude with a creative and inventive flare.
  • Adaptable, capable of working to tight deadlines and exacting standards.
  • Strong organisational skills with an ability to prioritise and work under pressure.
  • Demonstrated ability to learn quickly, applying new concepts and techniques.

Applicants should submit a CV and covering letter by email to jobs@nannatherapeutics.com Closing date will be 9am on the 14th of January 2019.

Scientist Synthetic Chemist - *Position closed*

Overview

Nanna Therapeutics Ltd. is a Cambridge, UK based biotech developing ground-breaking technologies for drug discovery. We are seeking a scientist to join our dynamic, multi-disciplinary team, focused on designing, making and expanding the synthetic repertoire of our encoded synthetic chemistry libraries for application in our totally integrated drug discovery platform.

We are seeking committed scientist with the ability to work across disciplines and function effectively as part of a diverse multidisciplinary team. Each member of our team is committed to continuous learning, expanding their skills base and growing expertise, both on the job and through specific courses and training as required.

This will be an exciting opportunity to join a dynamic company poised for growth at the cutting edge of drug discovery.

Specification

We are seeking a scientist with experience in the following key areas:

1. Qualification, Knowledge and Experience

* Experience in either synthetic, medicinal or combinatorial chemistry.

* A strong background in synthetic chemistry, experience with a wide range of reaction types and developing novel methods and synthetic routes.

* Use of analytical tools for reaction optimisation and trouble-shooting, HPLC, LC-MS, NMR, UV instruments and interpreting resulting analytical data.

* Experience in creating compound arrays, split and mix, encoded libraries or solid supported chemistry would be an advantage.

* Experience with one of the following techniques is desirable: microfluidics, computational chemistry, DNA sequencing, performing biological assays.

2. Essential Skills / Attributes

* Good interpersonal/communication skills, effective working as part of a team.

* High level of attention to detail, as well as demonstrated ability to work independently.

* Passion for science and a problem-solving attitude with a creative flare.

* Adaptable, capable of working to tight deadlines and exacting standards.

* Strong organisational skills with an ability to prioritise and work under pressure.

* Demonstrated ability to learn quickly, applying new concepts and techniques.

Applicants should submit a CV and covering letter by email to jobs@nannatherapeutics.com Closing date will be 30th November, 2018.

Scientist Synthetic Chemistry - *Position Closed *
Nanna Therapeutics Ltd. is a Cambridge, UK based biotech developing ground-breaking technologies to revolutionise drug discovery and we are leveraging this technology to treat mitochondrial and age-related diseases. As we continue to grow, we are seeking a skilled, enthusiastic scientist with experience in synthetic chemistry who can help grow our platform, utilising cutting edge technology to optimise reaction chemistry and help us build new, huge novel encoded chemistry libraries. Importantly you must be able to work across disciplines and function effectively as part of a multidisciplinary team. Each member of our team is committed to continuous learning, expanding their skills base and growing expertise, both on the job and through specific courses, conferences and training events with the chance to adopt additional roles and responsibilities as they develop. The ideal candidate will have a broad synthetic chemistry knowledge on which to call and experience with array or medicinal chemistry or encoded library technologies would be advantageous. However, a problem solver who can help develop new methods and techniques and is keen to learn, who will readily develop their skills and the develop the company’s capabilities by providing new ideas is ideal. The role is an exciting opportunity to join a dynamic company poised for growth at the cutting edge of drug discovery and help grow our chemistry team, within our multidisciplinary research group, developing both a new generation of drug discovery platforms and drugs to treat patients. Specification We are currently seeking a research scientist to join us with experience in Synthetic Chemistry Qualification BTec/HND/BSc/MSc in job-related field of study and 3+ years of relevant laboratory experience Or PhD in a relevant field with at least 1 year in an industrial setting or post-doctoral experience Knowledge and Experience
  • We expect that the successful candidate will have:
  • A strong background in synthetic chemistry and experience with a wide range of reaction types and developing novel methods and synthetic routes.
  • Use of analytical tools for reaction optimisation and trouble-shooting, HPLC, LC-MS, NMR, UV instruments and interpreting resulting analytical data.
  • Proven track record of working with other disciplines and teams in a constructive and collaborative manner
In addition, it would be desirable that the successful candidate has
  • Experience in medicinal or combinatorial chemistry
  • Experience in creating compound arrays, split and mix, encoded libraries or solid supported chemistry would be an advantage.
Essential Skills / Attributes
  • Passion for science together with a ‘can-do’ problem-solving approach
  • Ability and desire to learn new skills quickly and apply new concepts and techniques
  • Good interpersonal/communication skills able to work effectively across disciplines
  • An adaptable team player capable of working to tight deadlines and exacting standards
Strong organisational skills including ability to prioritise and work under pressure Please send a CV and covering letter by email to jobs@nannatx.com, although the closing date is April 15th we will review CVs weekly and call desirable candidates for interview as they come in and keep the job open until successful recruitment. Please no agencies or recruiters.

Contact Us

 

 

Contact Details Nanna Therapeutics Ltd The Merrifield Centre Rosemary Lane Cambridge CB1 3LQ Tel: +44(0)1223 247000 Email: info@nannatherapeutics.com Company no. 8328823